Final Programme

November 8, 2018 / Thursday
13:00-15:00Registration
15:00-15:45Opening ceremony
PLENARY LECTURE
Chair: Sonja Levanat
16:00-16:45Anton Berns (Netherlands)
"Mouse Models of Thoracic Cancers. What Do They Teach Us?" [EACR Sponsored Lecture]
16:45-17:10Coffee break
SECTION "Cell Signaling Networks"
Chairs: Vesna Musani, Ugo Cavallaro
17:10-17:40Ugo Cavallaro (Italy)
"Cancer Stem Cells: New Drivers and Mechanisms"
17:40-18:10Kristijan Ramadan (UK)
"DNA-Protein Crosslink Proteolysis Repair in Premature Ageing and Cancer"
Short talks:
18:10-18:25Iva I. Podgorski (Croatia)
"The Effect of SIRT3 Expression on Human Breast Cancer Cells in Normoxia and Hyperoxia"
18:25-18:40Željka Anzulović (Croatia)
"Digital Localization and Quantification of WNT-3A Signalling-edited Target Approach in a 21 Day Murine Model of Idiopathic Pulmonary Fibrosis"
18:40-19:30Welcome reception
November 9, 2018 / Friday
PLENARY LECTURE
Chair: Neda Slade
9:00-9:45Ivan Đikić (Germany)
"Ubiquitin and Autophagy Networks in Cancer Pathogenesis"
9:45-10:10Coffee break
SECTION "Cancer Genomics and Epigenetics"
Chairs: Petar Ozretić, Hubert Hackl
10:10-10:40Hubert Hackl (Austria)
"Genotype-Immunophenotype Correlation in Cancer"
10:40-11:10Rosa Karlić (Croatia)
"The Mutation Landscape of Cancers Serves as a Record of Early Malignant Transformation"
Short talks:
11:10-11:25Nina Milutin Gašperov (Croatia)
"DNA Methylation in Head and Neck Cancer and Oral Lesions"
11:25-11:40Filiz Bakar-Ates (Turkey)
"Cucurbitacin B Loaded Lipid Polymer Hybrid Nanocarriers Induced a Significant Decrease in Mitochondrial Membrane Potential in Breast Cancer Cells”
11:40-11:55Marta Popović (Croatia)
"Deciphering DNA-protein Crosslink Repair In Vivo Using Zebrafish Model"
12:00-12:30Rok Košir (Slovenia)
"Droplet Digital PCR (ddPCR) and the Detection of Somatic Mutations from Liquid Biopsy of Colorectal Cancer Patients" [Lecture sponsored by Labena d.o.o.]
12:30-13:30Lunch break
13:30:-14:30Poster session
SECTION "Metastasis and Invasion"
Chairs: Maja Herak Bosnar, Jonathan Sleeman
15:00-15:30Jonathan Sleeman (Germany)
"Microenvironmental Regulation of Metastasis"
15:30-16:00Erik Sahai (UK)
"Novel Mechanisms of Tumor-Stroma Crosstalk"
Short talks:
16:00-16:15Julienne K. Münzner (Germany)
"Taking Tumor Cells to the Third Dimension: 3D Models to Study Tumor Invasion and Metastasis"
16:15-16:30Ana Damjanović (Serbia)
"Anticancer Effect of Berberine Against 2D and 3D Cell Culture Models"
16:30-17:00Coffee break
SECTION "The Hedgehog-GLI Signaling Pathway Minisymposium"
Chairs: Maja Sabol, Fritz Aberger
17:00-17:30Peter G. Zaphiropoulous (Sweden)
"Hedgehog/GLI Signaling: Targets and Targeting"
17:30-18:00Fritz Aberger (Austria)
"Targeting Oncogenic Hedgehog Signaling Beyond Smoothened Inhibitors"
18:00-18:30Natalia Riobo-Del Galdo (UK)
"Non-canonical Hedgehog Signalling: Is It Implicated in Cancer?"
18:30-19:00Maja Sabol (Croatia)
"The GLI Code in Ovarian Cancer"
19:00-19:30Barbara Stecca (Italy)
"An Integrated Model of Hedgehog-GLI Molecular Functions in Cancer"
November 10, 2018 / Saturday
SECTION "Immuno-oncology"
Chairs: Božena Šarčević, Igor Aurer
9:00-9:30Igor Aurer (Croatia)
"Immunotherapy of Hematological Malignancies: A Success Story"
9:30-10:00Massimo Zollo (Italy)
"Targeting Medulloblastoma Metastatic Tumors via Immunomodulation Therapy"
Short talk:
10:00-10:15Julia Kargl (Austria)
"Neutrophil Elastase Induces Metastatic Phenotype In Vitro and In Vivo"
10:15-10:40Coffee break
SECTION "Targeted Therapies"
Chairs: Paula Podolski, Andreja Ambriović-Ristov
10:40-11:10Andreja Ambriović-Ristov (Croatia)
"Characterisation of Integrin alpha V-dependent Adhesome in Tumor Cells"
11:10-11:40Paula Podolski (Croatia)
"Targeted Therapies for HER2 Positive Metastatic Breast Cancer Patients"
Short talks:
11:40-11:55Jelena Grahovac (Serbia)
"Repurposing of the Angiotensin Inhibitor Telmisartan for Treatment of Pancreatic Ductal Adenocarcinoma and Malignant Melanoma"
11:55-12:10Josip Madunić (Croatia)
"Anticancer Effects of Apigenin in Human Breast Cancer Cells"
KEYNOTE LECTURE
Chair: Sonja Levanat
12:10-13:00Joseph Schlessinger (USA)
"The Role of Endocrine FGFs in Metabolism and Cancer"
13:00-13:30Closing ceremony and best poster awards [Sponsored by EACR]